
Hopes for new cancer vaccine
There have been encouraging results in melanoma vaccine trials run by US drug companies Moderna and Merck. The results are preliminary, but experts say they are the first positive late stage results for a cancer vaccine

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There have been encouraging results in melanoma vaccine trials run by US drug companies Moderna and Merck. The results are preliminary, but experts say they are the first positive late stage results for a cancer vaccine

A court in Damascus has handed down a death sentence to Wassim al-Assad, a cousin of deposed Syrian leader Bashar al-Assad. Wassim, an enforcer for the former regime, was found guilty of war crimes and crimes against hum

Meta denies claims it "chose to exploit" young people to hook them on its platforms. The trial, which begins this week, stems from a lawsuit filed in 2023 by 30 US states. California’s Attorney General Rob Bonta explains

Friends of Jason Arday have spoken of their shock, following the death of the academic. Also on the programme: a South Wales fire chief tells us why he needed to call in support from the army; five years after the Taliba

Counting is underway – but will Nigel Farage win, or Count Binface? We speak to the satirical alter ego of comedian Jon Harvey. Also in the programme: Nurses complain of "inhumane" conditions in hospitals as the heatwave

On a day when amateur eclipse chasers gaze toward the sky across Iceland and Spain, we join enthusiasts enjoying the spectacle in a packed London park. Also in the programme: two Palestinian families are besieged by Isra

The Prime Minister says he wants the killers of PC Andrew Harper to stay behind bars. How will he do it? We ask a senior law professor who advised the government on how to manage early prisoner releases. As Simon Levy is

At least 111 people have been killed and dozens more are injured after a powerful earthquake hit western Colombia, according to local officials. Dozens of buildings have collapsed. It comes less than two months after a d

Turkey, Saudi Arabia and Pakistan have signed a major defence pact in Mecca, saying an attack on one is an attack on all three. A former advisor to Turkey's president tells us what he thinks his country gets out of such

Prevent referrals in England and Wales were up 39% in the year to September 2025. It’s the highest number in a single year since records began in 2015. Where the age is known, 393 referrals were for children under 10, th

A former neo-Nazi, selected by the Conservatives to contest a council election, withdraws his candidacy A prominent professor who denied claims of plagiarism has quit his role at Cambridge Germany's Interior Minister has

More than 170 migrants have been rescued after the boat they were using to cross the English Channel caught fire. The boat was attempting to travel to the UK when its engine caught fire, according to the French authoriti

Heatwave conditions in Europe are due to continue for at least another week, pushing temperatures above 40C in many countries. Rivers have dried up in central Europe and wildfires have forced thousands to evacuate their

President Trump says the Board of Peace deal will result in the "complete disarmament" of Hamas in Gaza. Hamas says the handover of its heavy weapons depends on Israel ending "all forms of aggression" and withdrawing fro

North and Central America football associations join Uefa in rejecting Fifa’s proposal to sell stakes in its competitions to private investors. We explore the finance of football and hear reaction from a former chairman

The head of world football's governing body, FIFA, Gianni Infantino says controversial plans to sell off stakes in major competitions, including the World Cup, are an 'opportunity', not an 'obligation'. Also on the progr

President Volodymyr Zelensky has thanked Donald Trump for what he described as "firm US support" after a meeting at the White House. What's led to a thawing of their frosty relationship, and what might it mean for the Ru

President Emmanuel Macron has visited the fire-ravaged Gironde region of France. Some 220,000 people have been evacuated across the country because of wildfires. We speak to France's minister for international partnershi

The British prosecutor Karim Khan denies claims he had an improper sexual relationship with a junior staff member at the International Criminal Court. We hear reaction from Philippe Sands KC, who helped draft the treaty

The pause comes after criticism of the scheme from survivors and victims' families, including the widow of PC Andrew Harper who described the possibility of his killers' early release as "deplorable". We hear from the Ge
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