science
Hosted by Saloni Dattani & Jacob Trefethen · science · EN
Hard Drugs is a show by Saloni Dattani and Jacob Trefethen about medical innovation: how to speed it up, how to scale it up, and how to make sure lifesaving tools reach the people who need them the most. It is brought to you by Works in Progress.
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Contact path
Public web form
Booking probability
27%
Guest openness
Selective
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Signup to Generate a PitchHard Drugs is a show by Saloni Dattani and Jacob Trefethen about medical innovation: how to speed it up, how to scale it up, and how to make sure lifesaving tools reach the people who need them the most. It is brought to you by Works in Progress.
Hard Drugs is hosted by Saloni Dattani & Jacob Trefethen. The show has published 13 episodes to date.
Recent episodes include "Can we switch off diseases?" (2 October 2026, 76 minutes), "Are miracle drugs hiding in plain sight?" (24 July 2026, 152 minutes), and "Inventing the second malaria vaccine with Katharine Collins" (27 May 2026, 135 minutes).
Hard Drugs publishes roughly monthly, with episodes averaging 120 minutes across 13 episodes.
Booking probability for Hard Drugs is 27%, and the host is rated Selective on guests. Hard Drugs requires a Pod Score of 80 or higher. Hard Drugs's contact route on record: public web form.
The strongest fits for Hard Drugs are Scientific Research & Development. Hard Drugs has a science audience.
Saloni Dattani & Jacob Trefethen hosts Hard Drugs, a science podcast with 13 episodes published.
Our AI reads these to draft pitches. Use them as grounding for a pitch that cites a real guest and a specific topic.
Episode #12
What if treating diseases was as simple as telling your cells to stop making a harmful protein? That’s the premise of siRNA, a technology that silences genes without changing DNA. Just a single dose of siRNA can last...
Episode #11
GLP-1 drugs like Ozempic and Mounjaro have transformed the treatment of obesity as well as diabetes, help treat heart disease, kidney disease, sleep apnea, and maybe even Alzheimer’s. But they are far from the only...
<p>Malaria is caused not by a virus or bacterium, but by a complex, shape-shifting parasite that has evolved alongside us for millennia. This has made vaccine development a brutal challenge.</p><p>In this episode, Jacob...
Episode #9
<p>Heart disease is the leading cause of death worldwide, but it’s also one of medicine’s biggest success stories. Since the 1950s, the risk of dying from cardiovascular disease has fallen dramatically, thanks to public...
Episode #8
<p>Hepatitis B is a tiny virus that causes hundreds of thousands of deaths from liver disease and cancer each year. The vaccine against it became the first of many milestones: it was the first viral protein subunit...
Episode #7
<p>Before vaccines became routine, they were risky experiments. In this episode, Jacob and Saloni travel back to the world of smallpox, cowpox, and cow-based “vaccine farms” to see how scientists stumbled toward the...
Episode #6
<p>Artificial intelligence is transforming how we discover and develop new medicines. But how far can it really take us? In this episode, Jacob and Saloni trace the path of drug development from discovery to testing...
Episode #5
<p>What if you could design a protein never seen in nature? In this episode, Jacob and Saloni explore how researchers are using new tools like RFDiffusion, AlphaFold, and ProteinMPNN to ‘hallucinate’ entirely novel...
Episode #4
<p>Nature didn’t evolve all the proteins we need, but maybe artificial intelligence can help. Jacob and Saloni explore how tools like AlphaFold and ProteinMPNN are helping researchers re-engineer proteins, to make them...
Episode #3
<p>A hundred years ago, insulin was scraped from pig pancreases. Today, it’s made by bacteria in giant tanks. In the second part of a mini series on proteins, drug development and AI, Saloni tells the story of how...
<p>This episode kicks off a mini-series on proteins, drug development and AI. Saloni and Jacob explore the world of proteins, including how proteins fold into complex shapes, why that complexity matters and how crowded...
<p>Lenacapavir is a new HIV drug that blocks infections with an efficacy rate of nearly 100%, and it could completely change the fight against HIV worldwide. Saloni and Jacob talk about the development and prospects for...
Episode #1
<p>Hard Drugs is a new podcast about medical innovation: how to speed it up, how to scale it up, and how to make sure lifesaving tools reach the people who need them the most.</p><p>Presented and written by Saloni...
Recent guests on Hard Drugs. Study who booked and why before you pitch.
PhD student at King’s College London, Our World in Data
Open Philanthropy
Open Philanthropy
PitchCentric classifies Hard Drugs under these industries. Guests from them are the closest fit, and each links to the best podcasts in that industry.
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