Hosted by Inside Precision Medicine · 🇺🇸 US · EN · 44 episodes
Established thought leaders with verified media credentials.
Join host Jonathan D. Grinstein, PhD, North American Editor for Inside Precision Medicine , as he uncovers the stories behind the pioneers driving the precision medicine revolution. Behind the Breakthroughs features candid interviews with seasoned veterans and rising stars, exploring their origin stories and groundbreaking contributions advancing the frontiers of patient diagnosis, treatment, and care. In every episode, Jonathan goes beyond the science, diving deep into the personal and professional journeys of those striving to make these incredible new therapies more equitable and accessible globally. You'll discover how emerging technologies in molecular diagnostics, next-generation sequencing, genetic medicines (e.g., cell and gene therapies), and AI/ML are transforming treatment and bringing precision medicine closer to the forefront of healthcare. Whether you’re a researcher at a large pharma company or small biotech startup, a clinician at a major h
Inside Precision Medicine hosts Behind the Breakthroughs, a technology show with 44 episodes published.
Philippe Pouletty, MD, is one of Europe’s most successful life sciences entrepreneurs, having spent more than 30 years building category-leading biotechnology and medical technology companies from breakthrough scientific
While growing up during the polio era, Arthur Caplan, PhD, saw doctors hide painful truths from families and children, which sparked his lifelong questions about power, protection, and inequality in medicine. In this epi
Brain-computer interfaces have gained widespread attention largely for assistive applications, but Carolina Aguilar sees their greatest potential in directly treating neurological disease. Through INBRAIN Neuroelectronic
Matthew Rabinowitz, PhD, moved from engineering to medicine after his Human Genome Project work, motivated by both scientific insight and personal loss that exposed the limits of existing genetic diagnostics. He founded
Precision medicine promises individualized care through data, but progress remains fragmented. Clinical, genomic, and imaging data are siloed, limiting real-world use. Jurgi Camblong, PhD, founded SOPHiA Genetics to inte
As an Origination Partner at Flagship Pioneering, Molly Gibson, PhD, co-founded her first company, Generate:Biomedicines, in 2018, where she made her mark by developing models that design novel proteins—work that has alr
Xenotransplantation has long been a scientifically promising but ethically complex field, overshadowed by its limited practicality despite the growing shortage of transplantable organs and the urgent needs of patients. R
Traditional drugs usually inhibit specific protein sites, but many disease-causing proteins lack accessible or unique motifs, leaving them “undruggable.” Targeted Small-molecule drugs have long been the quiet workhorses
Cancer Research Institute CEO Alicia Zhou, PhD, traces her path from teenage lab technician to leader in cancer immunotherapy. Trained at MIT and Dana-Farber, she worked on The Cancer Genome Atlas before moving to indust
CRISPR has crossed a turning point, evolving from an experimental tool into a platform delivering FDA-approved therapies and on-demand patient treatments that correct disease at its source. Brad Ringeisen, a former DARPA
Cancer immunotherapy evolved through decades of research, with watershed moments like checkpoint inhibitor approvals and the first CAR T trial results reshaping expectations. For Zachary Roberts, MD, PhD, witnessing CAR
Geroscience sits between hype and skepticism, with headlines swinging from dubious mouse-life supplements to ethically distant fantasies like organ or head transplants. Yet precision medicine has been turning science fic
In this episode, I’m joined by Kevin Davies, PhD, Director of Professional Media Content Development at Sage Publications and acclaimed author of Editing Humanity, one of Jennifer Doudna’s favorite books on CRISPR. We ex
Precision medicine isn’t just molecular—it’s anatomical. Even as gene editing advances, many conditions still demand exquisitely targeted surgical care. That’s the world envisioned by Stereotaxis CEO David Fischel, where
Katherine Stueland’s early advocacy—raising money for genetic disease research as a child—shaped her belief that genomic insight can change lives. As CEO of GeneDx, she has refocused the company on high-need conditions,
When Rahul Gupta, MD, MPH, stepped down in January 2025 as Director of the White House Office of National Drug Control Policy, he closed a historic chapter as the first physician and first immigrant to serve as America’s
If you work in biotech, the name Langer likely rings a bell. Robert Langer—the MIT legend behind Moderna and dozens of biotech startups—has become synonymous with innovation. Now, a new Langer is stepping forward. Michae
When a rare genetic mutation left baby KJ without any treatment options, scientists and regulators confronted a profound ethical question: should medicine move fast enough to save a single child? For geneticist Vanessa A
Shana Kelley, PhD, embraces bold, science-fiction-like challenges, such as developing real-time technologies to monitor immune activity—work that demands cross-disciplinary expertise, flexible funding, and visionary lead
Mara Aspinall has long been a leader in precision medicine, championing diagnostics as vital to better treatments and saving lives. She built Genzyme Genetics into the nation’s top testing business, later acquired by Lab
Dr. Arthur Caplan
founding head of the Division of Medical Ethics · NYU Grossman School of Medicine
1 appearance on this show
Mike Curtis
President and CEO · Dallas Morning News
1 appearance on this show
Jennifer Doudna
Nobel Laureate · Innovative Genomics Institute
1 appearance on this show
Robert Langer
Institute Professor & Co-Founder of Moderna · MIT Langer Lab
1 appearance on this show
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Behind the Breakthroughs is hosted by Inside Precision Medicine. The show is categorised under technology (science) and has published 44 episodes.
Behind the Breakthroughs has published 44 episodes.
Behind the Breakthroughs regularly covers technology, science, health. It sits in the technology category, with a science focus.
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