Your Fertility Pharmacist

The most rigorously designed trial (to date) of intraovarian PRP demonstrated no improvements in # of mature oocytes obtained or # of live births versus no injections.

Resources Bronson R. and Kruljac I, Butorac D, Vrkljan M. and Legro RS, Zhang H; Eunice Kennedy Shriver NICHD Reproductive Medicine Network. Letrozole or clomiphene for infertility in the polycystic ovary syndrome. N...

A new study examines the associations between COVID-19 infection with pregnancy and miscarriage rates, looking at the first ten weeks after fresh embryo transfer.

A study compared fertility and sexual markers in obese men with low testosterone and erectile dysfunction who took liraglutide, uFSH + HCG, or testosterone. These men were separated into three groups based on their...

A recent study compared GnRH antagonists in egg donor ovarian stimulation cycles. The first drug is a newer agent, elagolix (Orilissa), that is taken as a tablet at night. The older drug is an injectable agent called...

A new trial tested a new way to give FSH to improve ovarian function in obese women without PCOS who are struggling to conceive. Resources Borgert BJ, Bacchus MW, Hernandez AD, Potts SN, Campbell KJ. The availability of...

New study on combining low-dose dexamethasone with letrozole in women with PCOS who failed to ovulate with letrozole alone. This study looked at ovulation, pregnancy, and live birth rates and took place at the Mayo...

Women report their use of herbs and supplements to a fertility clinic that assesses their herb-drug interactions. Resources Friedman J, Sheeder J, Lazorwitz A, Polotsky AJ. Herbal supplement use among reproductive-aged...

Does vaginal progesterone prevent miscarriages after early pregnancy bleeding? The research world has yet to agree, but a recently published Australian study (aka "the STOP trial") attempted to tackle this question...

This is the first randomized controlled multi-arm trial comparing how three hCG trigger doses impact endogenous progesterone levels in IVF- fresh embryo transfer cycles. Resources Abdalla HI, Ah-Moye M, Brinsden P, Howe...

This is the first meta-analysis published in seven years to examine dose-response associations between caffeine or coffee consumption and pregnancy loss. Resources Blehar MC, Spong C, Grady C, Goldkind SF, Sahin L...

This is the first study to test the use of vaginal tadalafil on endometrial thickness and pregnancies in women using IVF to conceive. Resources Balduyck J, Ameye A, Decleer W. Effect of vaginal/oral tadalafil on...

A recent randomized controlled trial compares ovarian stimulation protocols (standard vs. tamoxifen vs. letrozole) for freezing oocytes or embryos used in women diagnosed with breast cancer.

A recent well-designed American trial asked women with PCOS and obesity to take either placebo or GLP-1 agonist. 1/3 of participants were African-American and 2/3 were Caucasian. Most women had a goal of pregnancy...

An overview of research on women who completed ICSI, IVF, and/or embryo transfer while actively or recently testing positive for SARS-CoV-2 (COVID-19).