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Hosted by ISSCR · 🇺🇸 US · EN-US · 50 episodes
Established thought leaders with verified media credentials.
Stem cell science has catapulted to the forefront of biomedical research over the last decade, bringing with it the potential to transform human health and the treatment of devastating diseases and disorders. Janet Rossant, an internationally recognized stem cell pioneer and the dynamic editor-in-chief of Stem Cell Reports, explores basic discoveries in stem cell research and its application. Dr. Rossant goes “beyond the paper,” bringing authors together to draw new insights and explore the questions and creativity that drive new breakthroughs. Stem Cell Reports, published by the International Society for Stem Cell Research (ISSCR), is an open-access, peer reviewed journal that supports the field of stem cell research and regenerative medicine.
ISSCR hosts The Stem Cell Report with Janet Rossant, a science show with 50 episodes published.
Bosma arhinia microphthalmia syndrome (BAMS) is a rare genetic disorder resulting in babies born without a nose, along with eye and reproductive anomalies. Our guests today investigated the developmental basis of this di
Acute respiratory distress syndrome (ARDS) induced by COVID-19 was a leading cause of severe illness and death during the pandemic, driven by an intense innate immune response, hyperinflammation, and a decrease in lympho
Five years ago, The Stem Cell Report set out with a simple goal: to bring the science, the people, and the stories behind stem cell research into one conversation. Since then, the field has advanced at an extraordinary p
Our guests today created new lab models to study Merkel cells using mouse whisker tissue cultures, mouse skin organoids, and human skin organoids. These models allowed them to study Merkel cells as they develop, validate
Human pluripotent stem cells (hPSCs) are transforming the study of biology and disease by enabling scientists to grow large amounts of specific cell types in the lab that were once difficult to obtain. Our guests today f
Epigenetic regulation of gene expression is an important mechanism in development and disease. N6-methyladenosine (m6A) is one of the most prevalent epigenetic modifications for RNA and has been shown to play critical ro
The human intestinal epithelial barrier comprises diverse proliferative, secretory and absorptive cell types that facilitate nutrient digestion and absorption and protect against harmful environmental agents. The barrier
The blood-brain barrier (BBB), formed by brain endothelial cells, pericytes, and astrocytes, is organized into a neurovascular unit that regulates the exchange of proteins between blood circulation and brain parenchyma.
Hematopoietic stem cells (HSCs) normally reside in the bone marrow niche but can traffic across the bone marrow endothelium into the bloodstream to populate different niches. This process of HSC mobilization from the bon
The role of neuronal influences on cancer pathogenesis and progression is increasingly appreciated in the nervous system. Neurons have been shown to enhance the proliferation and migration of gliomas, a glial-derived tum
Skeletal muscle is one of the most abundant tissues in the human body, representing approximately 40% of body weight. Under certain circumstances, skeletal muscle can be regenerated through satellite cells, a reservoir o
The potential of pluripotent stem cells and the ability to scale and differentiate them to generate large numbers of enriched cell populations has created new opportunities and approaches to treat human disease. Preclini
Parent-specific epigenetic marks (imprints) leading to parent-specific gene expression are crucial for normal growth and development, yet their mechanisms of establishment and maintenance are not fully understood. In hum
The mature lung in both humans and mice is highly vascularized, with approximately 30% of all cells being endothelial cells (ECs). The blood vessels have a physiological role in gas exchange within the tissue, but the va
In this special edition of the podcast, we will talk with the new Editor-in-Chief Janet Rossant and hear about her vision for the journal, its promising future, and what she sees as some of the exciting prospects over th
During the last decade, advances in genome editing and pluripotent stem cell (PSC) culture have let researchers generate edited PSC lines to study a wide variety of biological questions. However, abnormalities in cell li
The ability of human pluripotent and somatic stem cells to differentiate into multiple cell types of the human body makes them uniquely useful to model human development and disease. As a result, these cells are shared,
Pluripotent stem cells are defined, in part, by their potential to generate cell types from all three embryonic germ layers. However, it is well known within the field that there is variability in developmental potential
Epigenetic clocks based on tissue DNA methylation analysis have emerged as robust and powerful biomarkers of aging. This technology has allowed scientists to investigate how diseases affect the aging process, to evaluate
Those who study neurological diseases and their underlying cellular and molecular mechanisms have a number of scientific models at their disposal. In vivo animal models, particularly those bearing targeted genetic modifi
Shifeng Xue
National University of Singapore
1 appearance on this show
Elmira Safaie Qamsari
Ottawa Hospital Research Institute
1 appearance on this show
Duncan Stewart
Ottawa Hospital Research Institute and University of Ottawa
1 appearance on this show
Clare Parish
The Florey Institute of Neuroscience and Mental Health and University of Melbourne
1 appearance on this show
Martin Pera
The Jackson Laboratory
1 appearance on this show
Lawrence Goldstein
University of California San Diego
1 appearance on this show
Charles Murry
University of Washington
2 appearances on this show
Joriene C. de Nooij
Columbia University
1 appearance on this show
Srimonta Gayen
Indian Institute of Science
1 appearance on this show
Renée Moerkens
Ombion
1 appearance on this show
Sebo Withoff
University of Groningen
1 appearance on this show
Roberto Villaseñor
Roche Innovation Center in Basel
1 appearance on this show
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The Stem Cell Report with Janet Rossant is hosted by ISSCR. The show is categorised under science (life) and has published 50 episodes.
The Stem Cell Report with Janet Rossant has published 50 episodes.
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Episodes of The Stem Cell Report with Janet Rossant average 43 minutes. a focused format where a clear narrative arc and tight preparation matter most.
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