
When Sepsis Hits the Lungs
Sepsis doesn’t just overwhelm the body, it can turn the lungs into ground zero for multi-organ dysfunction. In this episode, host Nicole Kupchik sits down with Dr. Julie Bastarache to explore how sepsis triggers Acute Re

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Hosted by Sepsis Alliance · 🇺🇸 US · EN · 17 episodes
Established thought leaders with verified media credentials.
Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns. Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR. Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in t
Sepsis Alliance hosts The Sepsis Spectrum, a health show with 17 episodes published.

Sepsis doesn’t just overwhelm the body, it can turn the lungs into ground zero for multi-organ dysfunction. In this episode, host Nicole Kupchik sits down with Dr. Julie Bastarache to explore how sepsis triggers Acute Re

Acute kidney injury (AKI) is far more dangerous and complex than previously understood. In this episode, host Nicole Kupchik sits down with Dr. Gonzalo Matzumura to break down what really happens inside the kidneys durin

Host Nicole Kupchik is joined by Dr. Kaveh Hoda to unpack one of the most overlooked drivers of sepsis: the gut. Often called “the motor of MODS,” the GI tract can push the body toward recovery, or accelerate systemic co

In this episode, Nicole Kupchik sits down with Dr. Craig Jenne to unravel how the liver’s immune response shifts during sepsis. Together, they explore how an organ known for detoxifying and defending the body can actuall

What if the key to controlling inflammation, and even saving lives from sepsis, lies not in the bloodstream, but in the brain? In this episode, Nicole Kupchik talks with Dr. Kevin J. Tracey, President and CEO of the Fein

When sepsis strikes, the damage doesn’t always end with the infection. Nicole Kupchik is joined by Dr. Mitchell Elkind from the American Heart Association to explore how inflammation during sepsis can overwhelm the cardi

Season 2 is just around the corner for The Sepsis Spectrum! In this special bonus episode, Nicole Kupchik reflects on what we learned last season, how cancer can’t keep her away, and what’s next for the pod. Joining Nico

What you don’t track, you can’t fix, and too often, we’re not even looking. Nicole is joined by sepsis survivors Dr. Hilary Spangler and Jackie Duda, along with pediatric ICU nurse-scientist Dr. Mallory Perry-Eaddy, for

When crisis hits every layer of care, how do you keep patients feeling human? Nicole is joined by Dr. Mark Mikkelsen and sepsis survivor Katy Grainger for a raw and powerful conversation for a raw and powerful conversati

Sometimes what we call prevention is really just harm repackaged. Nicole, Dr. Hudson Garrett, and Armando Nahum dig into the paradoxes of infection control, where well-meaning efforts can produce unseen consequences. The

How can we diagnose what we haven’t yet defined? Nicole welcomes Dr. Shamim Nemati and Dr. Gabriel Wardi to explore how artificial intelligence (AI) is reshaping sepsis detection. They dig into why existing definitions f

What if the way we’re trained to recognize sepsis is part of the problem? Nicole sits down with Kathleen Vollman to unpack how clinician education, documentation habits, and broken workflows contribute to missed or delay

Hospital-onset sepsis presents a complex and urgent challenge at the intersection of healthcare-associated infections (HAIs), antimicrobial resistance (AMR), and clinical decision-making. Nicole welcomes Dr. Jennifer Gin

Can pre-hospital teams catch sepsis before the hospital even sees it coming? Nicole sits down with EMS thought leader Eric Bauer to break down how tools like capnography, lactate testing, and passive leg raise are transf

Can standard sepsis protocols catch what the gut already knows? In this conversation, Nicole sits down with Dr. Laura Kahn to explore how the microbiome could transform our understanding of sepsis, antimicrobial resistan

Unpack the critical links between infection, antimicrobial resistance, and sepsis with host Nicole Kupchik, and learn how together, they’re placing intense strain on public health systems, communities, and the broader so

~ SERIES PREMIERES JUNE 17, 2025 ~ If a microbial mutation falls in a bloodstream forest… does it make a sound? When she’s not pondering weird stuff like that, Nicole Kupchik (Critical Care RN, CNS) is busy investigating
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The Sepsis Spectrum is hosted by Sepsis Alliance. The show is categorised under health (fitness) and has published 17 episodes.
The Sepsis Spectrum has published 17 episodes.
The Sepsis Spectrum regularly covers health, fitness, medicine. It sits in the health category, with a fitness focus.
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Episodes of The Sepsis Spectrum average 38 minutes. a focused format where a clear narrative arc and tight preparation matter most.
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