The Open Loop with Chay Carter

Neurotechnology is moving fast, but the real story is how it gets built, tested, funded, and scaled. On The Open Loop, we explore the people, companies, and ideas shaping the future of neurotechnology, with honest conversations on what’s being built, what’s working, what’s difficult, and where the industry is really heading next. Hosted by Chay Carter, Founder of Carter Sciences and Reccy Neuro, the podcast brings together founders, researchers, operators, investors, and industry leaders building at the intersection of neuroscience, healthcare, and technology. Expect practical, unfiltered insight on: 🔹 Building neurotech companies from research to commercialisation 🔹 Brain-computer interfaces, neuromodulation, neuro-AI, and emerging technologies 🔹 Investment, regulation, and the realities of scaling in healthcare 🔹 The people, challenges, and decisions shaping the future of the industry If you work in neurotechnology, neuroscience, healthcare innovation, or emerging technology, and want to understand what’s actually happening inside the industry, this is for you.

The Open Loop with Chay Carter is a science podcast hosted by Unknown Host, with 18 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Unknown Host hosts The Open Loop with Chay Carter, a science show with 18 episodes published.

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  The Open Loop with Chay Carter

  From Google X to NextSense: Building Brain-Sensing Smartbuds with Jonathan “JB” Berent

  Sep 10, 202640 min

  In this episode of The Open Loop, Chay Carter is joined by Jonathan “JB” Berent, Founder and CEO of NextSense. JB shares the story behind NextSense, from his early fascination with sleep and lucid dreaming to a Google X project exploring deep sleep enhancement, in-ear EEG, and brain-sensing wearables. We explore why the ear is such a compelling form factor for brain data, how NextSense is building smartbuds for sleep, focus and calm, and what it takes to turn advanced neurotechnology into a consumer product people actually use. We also discuss lucid dreaming research, acoustic stimulation, fundraising, product-market fit, manufacturing, ARPA-H’s REST programme, and future directions including more sensors, tVNS, and closed-loop sleep modulation. Key takeaways: Why NextSense built around in-ear EEG and smartbud form factor How a Google X sleep project evolved into a consumer neurotech company Why longitudinal brain data could shape the next generation of wearables What founders need to understand about product-market fit in consumer neurotech How closed-loop sleep modulation, audio and future sensors could expand the platform Guest: Jonathan “JB” Berent Founder and CEO, NextSense LinkedIn: https://www.linkedin.com/in/jonathan-berent/ Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Key Chapters: 00:39 Introduction to NextSense and Brain-Sensing Smartbuds 01:40 From Stanford, Lucid Dreaming and Google to NextSense 04:56 Lucid Dreaming, EEG and Dream Communication 07:46 Learning Neuroscience and Building at Google X 11:56 Spinning NextSense Out of Google 14:54 Fundraising, Consumer Neurotech and Investor Challenges 21:53 Product-Market Fit and the Toothbrush Test 27:28 Why NextSense Chose Earbuds for Brain Data The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/

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  The Open Loop with Chay Carter

  Scaling Interventional Psychiatry with William Sauvé

  Sep 2, 202645 min

  In this episode of The Open Loop, Chay Carter is joined by William Sauvé, MD, Chief Medical Officer at Osmind. William shares his journey from Navy psychiatry and combat mental health care to TMS, interventional psychiatry, Greenbrook, and his current work helping scale mental health infrastructure at Osmind. We explore how psychiatry can move beyond traditional medication management, the access challenge facing mental health care, and the role of treatments like TMS, ketamine, esketamine, and emerging psychedelic therapies. We also discuss real-world evidence, fMRI-guided TMS, accelerated treatment protocols, REMS workflows, psychiatric EHRs, and why interventional psychiatry could become a force multiplier for mental health care. Key takeaways: Why mental health care needs a “force multiplier” to meet patient demand How TMS has evolved from early adoption challenges to broader clinical use Why targeting, precision and real-world evidence matter in brain stimulation How Osmind supports workflows for TMS, ketamine and esketamine clinics Why emerging psychedelic therapies could change the logistics of psychiatric care Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guest: William Sauvé, MD Chief Medical Officer, Osmind LinkedIn: https://www.linkedin.com/in/william-sauv%C3%A9-md-45009813/ The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/

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  The Open Loop with Chay Carter

  At-Home Brain Stimulation for Depression with Balder Onarheim

  Aug 27, 202646 min

  In this episode of The Open Loop, Chay Carter is joined by Balder Onarheim, Founder and CEO of PlatoScience. Balder shares his journey from the Norwegian army and engineering design into creativity research, brain stimulation, and building at-home tDCS devices for mental health care. This is a practical conversation about transcranial direct-current stimulation, depression, neuroplasticity, usability, regulation, and what it takes to make brain stimulation safe and accessible outside the clinic. We explore how PlatoScience approaches medical-grade at-home tDCS, why the company works through clinicians, and how design, aesthetics, treatment adherence, and patient experience all shape the future of neuromodulation. Key takeaways: Why PlatoScience is focused on at-home tDCS for depression How tDCS changes neuronal thresholds without forcing brain activity Why medical-grade usability matters for patient adherence Why Balder believes mental health care should keep a human in the loop How regulation could shape the future of non-invasive brain stimulation Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guest: Balder Onarheim Founder and CEO, PlatoScience LinkedIn: https://www.linkedin.com/in/baldero/ Learn more about PlatoScience: https://www.platoscience.com/ Key Chapters: 00:39 Introduction to PlatoScience and At-Home tDCS 01:55 From the Norwegian Army to Brain Stimulation 05:51 From Biohacking to Medical-Grade tDCS 07:39 Depression, Ageing and Neurodivergence 09:50 How tDCS and TES Work 16:32 PlatoScience’s Device and Clinician-Led Model 29:25 Design, Treatment Sessions and Patient Usability 38:54 EU Regulation and the Future of Brain Stimulation The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/

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  The Open Loop with Chay Carter

  What Neurotech Can Learn from Cardiac Digital Health with Ken Nelson

  Aug 19, 202640 min

  In this episode of The Open Loop, Chay Carter is joined by Ken Nelson, Board Member, investor, venture partner, and advisor across multiple cardiac, digital health, AI, and neurotechnology companies. Ken shares his journey from corporate finance into medical devices, cardiac rhythm management, remote patient monitoring, venture investing, and board roles across companies including Epitel, StimCardio, Echo IQ, HeartBeam, Acarix, and Happitech. This is a practical conversation about what neurotechnology can learn from cardiac digital health, from remote monitoring and AI diagnostics to patient-friendly wearables and predictive care. We also explore Epitel’s work in long-term EEG monitoring, the future of brainwave data, wearable neuromodulation, and why the next phase of neurotech may mirror many of the lessons already learned in cardiac care. Key takeaways: Why cardiac digital health has helped pave the way for remote neuro monitoring How Epitel is changing the standard of care in long-term EEG monitoring Why patient-friendly wearables can improve data quality and clinical yield How AI and predictive analytics could support earlier intervention in heart and brain health Why the future of healthcare may depend on combining cardiac, neurological, and biometric data Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guest: Ken Nelson Board Member, investor, venture partner, and advisor LinkedIn: https://www.linkedin.com/in/ken-nelson-56aaa34/ Key Chapters: 00:39 Introduction to Ken Nelson 01:04 From Finance to Cardiac Medical Devices 09:57 iRhythm, Digital Health and Remote Monitoring 13:18 What Neurotech Can Learn from Cardiac Monitoring 16:05 Wearable Neuromodulation and StimCardio 18:04 Multi-Parameter Monitoring and Predictive Care 21:01 Epitel and Long-Term EEG Monitoring 26:53 Brain Data, AI and Actionable Reports The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/

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  The Open Loop with Chay Carter

  TMS, Neuroplasticity and Precision Psychiatry with Corey Keller, MD, PhD

  Aug 12, 202643 min

  In this episode of The Open Loop, Chay Carter is joined by Corey Keller, MD, PhD, Associate Professor at Stanford University and Co-Founder of Alto Neuroscience. Corey shares his journey from engineering and intracranial brain recordings in epilepsy patients to psychiatry, TMS, neuroplasticity, and precision mental health. This is an interesting conversation about what brain stimulation can do today, what we still do not fully understand, and why the next phase of psychiatry may depend on better ways to measure how treatments change the brain. We explore Corey’s work using invasive and non-invasive brain recordings, his role in the early development of Alto Neuroscience, and why EEG, TMS, fMRI, brain state, dosing, timing, and treatment personalisation all matter in the future of neuromodulation. We also discuss wearable neurotechnology, brain foundational models, accelerated TMS protocols, esketamine, clinical translation, advisory work, mentorship, and why Corey describes himself as a “skeptical neuroscientist” testing the questions that still need to be answered. Key takeaways: Why TMS may still be under-personalised despite its clinical impact How EEG and brain recordings could help guide psychiatric treatment decisions Why neuroplasticity needs to be measured at the millisecond level How Alto Neuroscience emerged from work on EEG biomarkers and treatment selection Why the future of mental health neurotechnology depends on better science, not just better devices Guest: Corey Keller, MD, PhD Associate Professor at Stanford University Co-Founder of Alto Neuroscience LinkedIn: https://www.linkedin.com/in/corey-keller-stanford/ Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more: https://neuro.reccy.dev/

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