The Loop Podcast: Peptides, Longevity & Women’s Wellness

A podcast exploring peptides, women's health, longevity strategies, and modern wellness—through real conversations and lived experience. Hosted by Stephanie Gambetta, The Loop Podcast breaks down what’s actually working when it comes to feeling better, aging well, and taking ownership of your health.

The Loop Podcast: Peptides, Longevity & Women’s Wellness is a health podcast hosted by Stephanie Gambetta, with 73 episodes on record and a Required Pod Score of 80.

Stephanie Gambetta hosts The Loop Podcast: Peptides, Longevity & Women’s Wellness, a health show with 73 episodes published.

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  Episode #73

  EP 73: DEXA Scans, GLP-1s & The Truth About Muscle Loss | Aabid Farukhi | The Loop Podcast Ep. 73

  Oct 1, 20261 hourS1

  Stephanie Gambetta starts this episode with a solo update on what’s happening with Loop Health , her current peptide routine, the upcoming Loop Beauty line, and some of the changes she’s making in her own health at 51. She talks about building muscle in midlife, improving her sleep during menopause, prioritizing recovery, monitoring her blood work, and the mitochondrial stack she’s currently using. She also gets personal about the realities of building Loop Health, navigating life without Instagram, experimenting with TikTok, and making more time for friendships, travel, and the things that actually fill her back up. Then Stephanie sits down with Aabid Farukhi , a board-certified musculoskeletal radiologist, to break down DEXA scans and why the number on your bathroom scale doesn’t tell the whole story. They explain how a DEXA scan measures muscle mass, body fat, visceral fat, bone density, and even muscle symmetry between different sides of your body. Stephanie also walks through her own DEXA results, including gaining a pound of muscle while microdosing a GLP-1, and shares why she uses these scans to see whether her training, nutrition, peptides, and lifestyle are actually changing her body composition. Stephanie and Aabid also dig into one of the biggest concerns surrounding GLP-1s: losing muscle and bone mass while losing weight . They discuss resistance training, protein, visceral fat, bone health during perimenopause and menopause, and why tracking body composition can give you a much clearer picture of your progress than obsessing over weight alone. Whether you’re using GLP-1s and peptides or simply trying to build muscle, lose fat, and stay strong as you age, this episode is about understanding what’s actually happening inside your body. This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing medications, peptides, supplements, hormones, or other treatments. Peptides & Compounds Discussed SS-31 MOTS-c 5-Amino-1MQ NAD+ Thymosin Alpha-1 KPV GLP-1 receptor agonists Glutathione GHK-Cu Progesterone Magnesium Creatine LOOPHEALTH20 to get 20% off a dexascan with Dexafit OC (https://www.oc.dexafit.com/)

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  Episode #72

  EP 72: Midlife Crisis or Midlife Awakening? The Psychology of Starting Over After 40 | Dr. Sarah Sarkis

  Sep 24, 20261 hourS1

  Psychologist Dr. Sarah Sarkis returns to The Loop Podcast to talk about the psychology of midlife and why the changes that happen in your 40s and 50s can feel so uncomfortable. Stephanie and Sarah break down the idea of a “midlife crisis” and look at what’s actually happening when your identity, relationships, career, family life, hormones, and priorities all begin shifting at the same time. Sarah explains why discomfort doesn’t necessarily mean something is wrong, how the things that worked earlier in life may need to be upgraded, and why the whispers telling you something needs to change can eventually become impossible to ignore. Stephanie also shares what this has looked like in her own life, from divorce and rebuilding her identity to the recent challenges with Instagram, postponing her Loop event, and unexpectedly finding a new creative outlet on TikTok. They talk about what happens when your growth makes the people around you uncomfortable, why progress includes plateaus and even periods of regression, dealing with comparison and rejection, grieving an old version of your life, and learning to keep moving when you have no idea exactly where you're headed. Sarah also shares a different way to think about whether a major life change is “working”: sometimes constantly measuring your progress is perfectionism disguised as excellence. Stephanie and Sarah also preview the upcoming Aspen retreat , where Sarah will help women explore the stories they’re carrying into midlife, decide which ones still serve them, and become more intentional about what they want the next chapter of their lives to look like. Join Steph & Dr. Sarkis at the Loop retreat ( http://www.theloopway.com/events/aspen ), $500 off exclusively for podcast listeners available here: https://buy.stripe.com/8x27sKfz30JKb1S7jo3gk01

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  Episode #71

  EP 71: HRT, Peptides & GLP-1s: What Women Need to Know About Menopause | Karen Martel |

  Sep 17, 20261h 2mS1

  Karen Martel, CEO of Midlife Solutions , joins Stephanie Gambetta for a candid conversation about perimenopause, menopause, hormone replacement therapy, peptides, GLP-1s, and what actually changes in a woman’s body during midlife. Karen shares how her own experience being pushed into early menopause at 42 changed the direction of her career, despite already working as a nutritionist and doing everything she thought was “right.” She and Stephanie break down the early signs of perimenopause, progesterone and estrogen loss, stubborn midlife weight gain, brain fog, mood changes, and why you can’t always diet, exercise, or biohack your way out of hormonal changes. Stephanie also opens up about her own HRT journey at 51, including progesterone, estrogen, testosterone pellets, and the changes she’s currently navigating. Together, she and Karen discuss why HRT and peptides can work together rather than compete, combining GLP-1s with optimized hormones, microdosing, food noise, preserving muscle, thyroid health, and why some women plateau on GLP-1s even at higher doses. They also get into starting HRT later in life, overdoing biohacking, wearable data, DEXA scans, peptide safety, and why women need individualized protocols instead of copying whatever someone else is taking online. Karen and Stephanie also challenge the idea that suffering through menopause deserves a badge of honor. The goal isn’t perfection or doing every wellness trend imaginable. It’s understanding your body, finding the right tools, and building a sustainable approach that helps you feel strong, confident, and healthy through the second half of life. Use code LOOP10 for 10% off at Midlife Solutions. Shop Midlife Solutions This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing hormones, medications, peptides, supplements, or other treatments. Peptides, Hormones & Compounds Discussed Hormone Replacement Therapy (HRT) Estrogen Progesterone Testosterone GLP-1 receptor agonists Retatrutide GHK-Cu TB-500 BPC-157 MOTS-c Tesamorelin Thyroid medication

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  Episode #70

  EP 70: GLP-1s, Peptides & Why Doing Everything Right Isn’t Working | Sienna Olson

  Sep 10, 20261h 1mS1

  Sienna Olson , founder of SLO Rx , joins The Loop Podcast for a conversation about what happens when you’re doing everything “right” but your body still isn’t responding. Sienna holds a Doctorate in Chiropractic and a Master’s in Sports Medicine, and her own journey from ski racing and bodybuilding to gaining 50 pounds in five months changed the way she thinks about metabolism, body composition, and women’s health. Today, she works with women who are juggling careers, families, and packed schedules but still wondering why their energy is low and their hard work isn’t showing up in the mirror. Her philosophy is simple: more isn’t better, right is. Stephanie and Sienna break down GLP-1s, peptides, protein, resistance training, body composition, and why simply increasing a dose or adding another wellness tool isn’t always the answer. They discuss tirzepatide versus retatrutide, microdosing, BPC-157, why Sienna takes a conservative approach to peptides, and how the scale can completely distort your perception of progress when you’re building muscle. They also get into comparison, consistency, sleep, finding a sustainable routine, and giving women permission to want to feel healthy, strong, confident, and hot without apologizing for it. It’s a conversation about getting away from quick fixes and finding the tools that actually fit your body and your life. Peptides & Compounds Discussed Tirzepatide Retatrutide GLP-1 receptor agonists BPC-157 Selank Semax Microdosing GLP-1s / peptide protocols This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing medications, peptides, supplements, training, or other treatments.

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  Episode #69

  EP 69: Facelifts, Peptides & What Actually Works After 40 | Dr. Jonathan Zelken

  Sep 3, 202654 minS1

  Plastic surgeon Dr. Jonathan Zelken returns to The Loop Podcast for a candid conversation about plastic surgery, peptides, aging, and the treatments that are actually worth your time and money. Stephanie opens up publicly about getting a deep plane facelift at 48, why she chose to do it before she felt like she “needed” one, and what the recovery was really like. Together, Stephanie and Dr. Zelken break down deep plane versus SMAS facelifts, fat transfer versus filler, Botox, buccal fat removal, rhinoplasty, breast augmentation, skin resurfacing, body contouring after weight loss, and why subtle results often require more work than social media makes it seem. Then they flip the script and put Stephanie in the expert seat for a rapid-fire round on peptides, GLP-1s, HRT, muscle building, sleep, libido, recovery, and injectable versus oral peptide therapy. Stephanie also challenges Dr. Zelken to try a new peptide and body-composition protocol before returning to the podcast later this year. It’s an honest, funny conversation about looking better, feeling better, and making informed choices without pretending there’s one right way to age. This episode is for educational purposes only and should not be considered medical advice. Always consult qualified medical professionals before undergoing surgery or beginning or changing medications, peptides, hormones, supplements, or other treatments. Peptides & Compounds Discussed BPC-157 TB-500 CJC-1295 Ipamorelin GHK-Cu GLP-1 receptor agonists Retatrutide Tesamorelin PT-141 Thymosin Alpha-1 Epitalon DSIP HGH / growth hormone Hormone Replacement Therapy (HRT)

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