business
Hosted by Mark Davison · business · EN-GB
Ever wondered how technology start-ups, well, start-up? For most founder entrepreneurs, it is the biggest experiment they'll ever run. Like most experiments, the result isn't known beforehand and it often doesn't work first time. On a bigger scale, how do big tech companies turn innovative science into profit? Mark Davison interviews founder scientists, executives, investors, communicators, and others in the technology start-up and corporate science ecosystems. Learn how great ideas turned into thriving businesses (or not) from those who made it happen (or didn't). Get business tips, lessons learned, and life lessons straight from the people who know. Inspiring, disastrous, funny: hear what life in a science-driven company is really like. Straight-talking, no nonsense, but conversational style. All technical content is explained for the non-specialist - you don't need a PhD or fluency in jargon and technobabble.
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Contact path
Public web form
Booking probability
29%
Guest openness
Selective
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Signup to Generate a PitchEver wondered how technology start-ups, well, start-up? For most founder entrepreneurs, it is the biggest experiment they'll ever run. Like most experiments, the result isn't known beforehand and it often doesn't work first time. On a bigger scale, how do big tech companies turn innovative science into profit?
The Big Experiment is hosted by Mark Davison. The show has published 27 episodes to date.
Recent episodes include "Tim Corcoran: Cosmetics from Cyanobacteria" (10 November 2025, 34 minutes), "From Jellyfish to Wound Healing with Dr Andrew Mearns-Spragg" (12 October 2025, 38 minutes), and "Jenny Barnett: New tests and drugs for schizophrenia" (10 August 2025, 39 minutes).
The Big Experiment publishes roughly monthly, with episodes averaging 40 minutes across 27 episodes.
Booking probability for The Big Experiment is 29%, and the host is rated Selective on guests. The Big Experiment requires a Pod Score of 80 or higher. The Big Experiment's contact route on record: public web form.
The strongest fits for The Big Experiment are Scientific Research & Development and Business & Management Consulting. The Big Experiment has a business audience.
Mark Davison hosts The Big Experiment, a business podcast with 27 episodes published.
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The Big Experiment
Is the answer to sustainable chemical manufacturing floating in our oceans? Ocean cyanobacteria, like plants, use sunlight as power to help them make complex chemicals. Traditional industrial chemistry requires a lot of...
Episode #25
What if the solution to chronic wound healing has been floating in our oceans for 600 million years? Jellyfish collagen isn't just different from the cow and pig-derived materials used in medicine today. It's actually...
The Big Experiment
Can neuroscience finally catch up with the complexity of mental illness? Society faces a huge and growing burden from mental illness and impairment. Schizophrenia, for example, is a bigger socioeconomic burden than all...
The Big Experiment
Forget drilling—what if diesel could be grown instead? In this episode we head into the world of engineered biology with Paul Beastall, CEO of HutanBio . He explains how his team is cultivating an oil-rich microalgae...
Episode #22
What if the future of computing isn’t silicon... but neurons? In this episode, we explore a radical new frontier where biology and technology come together — programming living neurons as processors. I am joined by Dr...
Episode #21
Three-quarters of women report that menstrual symptoms impact their daily performance, yet until recently, no one had looked at the brain's role in these symptoms. In this eye-opening episode I am joined by Emilė...
Episode #20
Electrical monitoring and stimulation could revolutionise diagnosis and treatment for some of the most aggressive brain cancers and intractable neurological diseases. In glioblastoma, a particularly aggressive brain...
Episode #19
Imagine that we could make tissues indistinguishable from those produced by humans or animals, at will, and at comparable cost to the natural products. With the rate of progress being made, it won’t be imaginary much...
Episode #18
In this episode of The Big Experiment, we are live, recording from the Synthetic Biology UK 2024 conference hosted by the Biochemical Society, at Hinxton Hall near Cambridge, home of the famous Genome Campus. Synthetic...
Episode #17
Weight loss drugs are in the spotlight. Obesity is a huge and potentially profitable problem, attracting lots of scientific and medical resources. But there are circumstances where avoiding weight loss is crucial and...
Episode #16
Heart valve surgery is one of the most complex procedures in medicine. Francis White and his company Heart Biotech Ltd are trying to change all of that, by making heart valves in a totally new way. This will make...
Episode #15
This episode went live on World Menopause Day. Menopause is an inevitable aspect of life for half of the global population, but one that requires far more study. New genomic insights could empower women with better...
The Big Experiment
What role does 3D genomics have in drug discovery? In this episode I am joined by Hazel Jones, CEO of Enhanc3d Genomics, to find out more about this cutting-edge technology. Hazel is a dynamic and flexible senior leader...
Episode #13
What does it take to get a new drug to market? I have been involved in the drug industry for 35 years. I’ve worked for big pharma like GlaxoSmithkline, contract research organisations (CROs) like Charles River and...
Episode #12
1 in 2 of us will be affected by dementia in our lives. Something so prevalent without a cure requires novel approaches for diagnosis. In this episode I am joined by Professor Zoe Kourtzi, from the University of...
Episode #11
Men’s fertility is falling and fast. In the last 50 years sperm counts are down by 60%. Yet this is still a topic that no one is really talking about. My guest in this episode, Lily Elsner, is the co-founder and CEO of...
Episode #10
This edition of The Big Experiment is a little bit different to the usual format. I'm on the road visiting the famous University of Cambridge Judge Business School to talk to people at the Ignite program. It’s an...
Episode #9
My son was diagnosed with type 1 diabetes at the age of 13. Which is why this episode is very close to my heart. There are big life-altering challenges for the patient and their family in managing type 1 diabetes. With...
Episode #8
The challenges of scientific entrepreneurship don’t end when you get funding. In fact, a whole new set of challenges arise, from finding labs, to building your team and more. In this episode I talk to Dr. Kärt Tomberg...
Episode #7
Would you have the guts to pitch directly to the customer to sell your idea? You need to be prepared to hear no a lot, and learn from the experience to adapt for the next time, to get the yes you need. This was the...
Recent guests on The Big Experiment. Study who booked and why before you pitch.
Managing Director, Marketing & Creative Services, Twin Eagles Wilderness School
neuroscientist with a PhD in brain imaging, researcher at King's College London, Final Spark
email marketing expert, Cumbria Wildlife Trust
CEO and Co-Founder, Jack Fertility
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