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聊聊Sci has a verified contact on file. Create a free PitchCentric account to access it and generate a personalised pitch in seconds. Research at least 3 recent episodes first and lead with a specific angle that serves their science audience.

Who is the host of 聊聊Sci?

聊聊Sci is hosted by 淼淼Elva. The show is categorised under science and has published 1,000 episodes.

How many episodes does 聊聊Sci have?

聊聊Sci has published 1,000 episodes.

What topics does 聊聊Sci cover?

聊聊Sci regularly covers science. It sits in the science category.

Is it hard to get booked on 聊聊Sci?

聊聊Sci is accessible for guests with genuine science expertise. A personalised, episode-aware pitch will still outperform a generic one every time.

Is 聊聊Sci currently accepting guest pitches?

聊聊Sci hasn't explicitly signalled guest openness in recent episodes. That doesn't rule out pitching. your hook just needs to be especially compelling and relevant to their recent content.

How long are 聊聊Sci episodes?

Episodes of 聊聊Sci average 23 minutes. a focused format where a clear narrative arc and tight preparation matter most.

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Our data rates 聊聊Sci's guest bar at 80/100 (Premium tier). Established thought leaders with verified media credentials. Sign in to PitchCentric to see how your own Pod Score compares against this show.

science

聊聊Sci

Hosted by 淼淼Elva · science · ZH-CN · 1,000 episodes

Audience: 9

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About this Podcast:

聊聊Science和Nature！

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What is 聊聊Sci?

聊聊Sci is a science podcast hosted by 淼淼Elva, with 1,000 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

About the host

淼淼Elva hosts 聊聊Sci, a science show with 1,000 episodes published.

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Recent episodes

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聊聊Sci
1579-鼠耳蝠基因组：长寿、抗癌与病毒适应性的演化机制
Sep 15, 202616 min
这项研究通过对鼠耳蝠属（Myotis）八个物种的高质量基因组测序，揭示了其长寿、抗癌及病毒耐受性的遗传基础。研究发现，这些蝙蝠对 DNA病毒和 RNA病毒展现出截然不同的演化适应机制，例如免疫因子 PKR 在物种间存在古老的拷贝数变异。分析表明，鼠耳蝠在演化过程中经历了与癌症抑制和 DNA损伤修复相关的基因正向选择，这解释了其远超同等体型哺乳动物的寿命。实验证明，长寿物种如小棕蝠具有更灵敏的细胞凋亡反应以清除受损细胞，体现了其在衰老与免疫上的协同演化。总之，这些数据为理解哺乳动物如何通过基因多效性实现疾病抵御与寿命延长提供了关键见解。 References: Vazquez J M, Lauterbur M E, Mottaghinia S, et al. Insights into longevity and virus-driven adaptation from Myotis bat genomes[J]. Nature, 2026: 1-10. 前往小宇宙评论区与主播互动
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聊聊Sci
1578-AGENTEX：自动化遗传密码原型设计与扩展
Sep 15, 202615 min
本文介绍了一种名为 AGENTEX 的自动化机器人平台，旨在通过无细胞翻译系统快速原型化并构建人工遗传密码。研究人员突破了长期以来认为tRNA末端必须为 CCA序列才能被氨酰化的传统认知，发现大肠杆菌氨酰-tRNA合成酶能够灵活地为多种非标准末端（如 CGA ）的tRNA充电。利用这一发现，他们开发了 tSCAN 技术以自动监测氨酰化效率，并结合工程化核糖体实现了正交翻译，有效避免了与天然系统的交叉干扰。该系统成功实现了遗传密码的压缩与重分配，能够将非标准氨基酸单体引入多肽合成。这项成果不仅为生物聚合物的高效合成开辟了新途径，也深化了人类对翻译系统演化逻辑的理解。 References: Radford F, Sapers N, Burgess H M, et al. Automated prototyping of genetic codes[J]. Nature, 2026: 1-11. 前往小宇宙评论区与主播互动
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聊聊Sci
1577-Malva：单细胞数据超快无参考序列检索平台
Sep 15, 202626 min
Malva 是一个旨在解决大规模单细胞及空间转录组数据搜索难题的计算平台。现有的细胞图谱通常依赖于预定义的参考基因组，难以直接检索原始序列、突变或病原体，而该工具通过无须参考基因组的索引算法实现了超快速查询。它包含一个持续扩展的索引数据库，涵盖了来自数千个实验的约 7400 万个细胞，使用户能够在数秒内跨研究检索特定的核苷酸序列。通过该平台，研究人员可以识别细胞类型、分析异构体使用情况并发现传统方法无法检测到的遗传变异或病毒感染。总之，该技术将静态的基因计数表转化为了动态且分辨率可达碱基级别的可搜索资源。 References: León-Periñán D, Karaiskos N, Rajewsky N. Ultrafast and reference-free sequence discovery in single-cell data[J]. Nature, 2026: 1-11. 前往小宇宙评论区与主播互动
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聊聊Sci
1576-癌症突变图谱：蛋白质组学引领的体细胞解析
Sep 14, 202629 min
这项研究通过整合 139,818 名癌症患者的基因组数据与蛋白质结构模型，构建了一个涵盖 173 个癌症相关基因的蛋白质基因组学分析框架。研究通过隐藏马尔可夫模型识别出基因中的 “显著突变区域” ，揭示了突变并非随机分布，而是集中在影响蛋白质功能的关键结构域或维持结构稳定性的三维核心区域。该框架不仅解析了不同癌症类型中基因失活或激活的分子机制，还阐明了无义介导的 mRNA 降解（NMD）对截断突变空间分布的约束作用。临床分析证明，位于这些显著区域内的突变与更强的致病性、基因表达变化及患者生存预后密切相关。这一研究成果为临床解释那些注释稀缺或存在争议的突变提供了标准化背景，有助于精准医疗中的患者分层。最终，研究团队通过 oncofold.org 提供了交互式资源，旨在助力全球科研人员更直观地理解突变在蛋白质结构中的功能意义。 References: Zhou Y, Chung W K, Dietlein F. Proteo-genomics-guided interpretation of somatic mutations in cancer genomes[J]. Cancer Cell, 2026. 前往小宇宙评论区与主播互动
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聊聊Sci
1575-腊样芽孢杆菌调控肝癌干性淋巴微环境增强免疫治疗响应
Sep 14, 202622 min
这篇文章研究了肝细胞癌中三级淋巴结构（TLS）的异质性，并鉴定出一种能预测免疫治疗效果的干性淋巴生态位（SLNs）。研究发现，这种生态位由 CD70+ ILC2s 和 TCF1+ Tpex细胞共同构成，其丰度直接影响PD-1/PD-L1抑制剂的疗效。研究揭示，肠道来源的蜡样芽孢杆菌能易位至肿瘤，通过分泌 PI-PLC 诱导内皮细胞释放 IL-33 。这种细胞因子通过代谢与表观遗传重塑激活ILC2s，进而促进SLNs的形成。实验证明，将 PI-PLC 或 rIL-33 与免疫检查点阻断疗法联合使用，能显著增强抗肿瘤免疫反应。这一发现为提升肝癌免疫治疗的临床获益提供了新的治疗靶点和策略。 References: Hu C, You W, Huang Y, et al. Intratumoral Bacillus cereus orchestrates stem-like lymphoid niches to potentiate immunotherapy response in hepatocellular carcinoma[J]. Cancer Cell, 2026. 前往小宇宙评论区与主播互动
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Every question we get asked before
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If you have a concern about deliverability, AI quality, data privacy, or whether this will actually work for your specific situation, it's probably answered below.

What is the difference between Founder Solo and Founder Pro?

How do agency tiers work?

What is a talent profile?

Can I switch plans later?

Yes, at any time. Upgrades take effect immediately; downgrades apply at the end of the current billing period. Contact support if you need help migrating between plan families.

Do you offer a free trial?

Every paid plan includes a 15-day free trial. Your card is saved at signup but you will not be charged until day 16. Cancel any time from your dashboard.

What happens if I cancel?

You keep access until the end of your current billing period. No charges after that. Your data is retained for 30 days in case you reactivate.

Is the 20% annual discount automatic?

Yes. Select Annual on the pricing toggle and the discounted price is applied automatically at checkout. The annual price shown is the full year cost.

What if I have more than 50 profiles or 20 clients?

That is our Enterprise tier. Contact our sales team and we will build a custom plan with volume pricing, a dedicated account manager, and SLA guarantees.

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聊聊Sci

About this Podcast:

Pitch Analysis

What is 聊聊Sci?

About the host

Recent episodes

1579-鼠耳蝠基因组：长寿、抗癌与病毒适应性的演化机制

1578-AGENTEX：自动化遗传密码原型设计与扩展

1577-Malva：单细胞数据超快无参考序列检索平台

1576-癌症突变图谱：蛋白质组学引领的体细胞解析

1575-腊样芽孢杆菌调控肝癌干性淋巴微环境增强免疫治疗响应

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Every question we get asked before
someone starts their trial.

聊聊Sci

About this Podcast:

Pitch Analysis

What is 聊聊Sci?

About the host

Recent episodes

1579-鼠耳蝠基因组：长寿、抗癌与病毒适应性的演化机制

1578-AGENTEX：自动化遗传密码原型设计与扩展

1577-Malva：单细胞数据超快无参考序列检索平台

1576-癌症突变图谱：蛋白质组学引领的体细胞解析

1575-腊样芽孢杆菌调控肝癌干性淋巴微环境增强免疫治疗响应

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Best industries to pitch 聊聊Sci for

Podcasts like 聊聊Sci

Every question we get asked before
someone starts their trial.

聊聊Sci

About this Podcast:

Pitch Analysis

What is 聊聊Sci?

About the host

Recent episodes

1579-鼠耳蝠基因组：长寿、抗癌与病毒适应性的演化机制

1578-AGENTEX：自动化遗传密码原型设计与扩展

1577-Malva：单细胞数据超快无参考序列检索平台

1576-癌症突变图谱：蛋白质组学引领的体细胞解析

1575-腊样芽孢杆菌调控肝癌干性淋巴微环境增强免疫治疗响应

Advertisers on this show

Best industries to pitch 聊聊Sci for

Podcasts like 聊聊Sci

Every question we get asked beforesomeone starts their trial.

聊聊Sci

About this Podcast:

Pitch Analysis

What is 聊聊Sci?

About the host

Recent episodes

1579-鼠耳蝠基因组：长寿、抗癌与病毒适应性的演化机制

1578-AGENTEX：自动化遗传密码原型设计与扩展

1577-Malva：单细胞数据超快无参考序列检索平台

1576-癌症突变图谱：蛋白质组学引领的体细胞解析

1575-腊样芽孢杆菌调控肝癌干性淋巴微环境增强免疫治疗响应

Advertisers on this show

Best industries to pitch 聊聊Sci for

Podcasts like 聊聊Sci

Every question we get asked beforesomeone starts their trial.

Every question we get asked before
someone starts their trial.

Every question we get asked before
someone starts their trial.