MS-Selfie

<p>Last week, a colleague sent me the publication below (van Laar et al., 2024).</p><p>The publication highlights that while gender equality efforts traditionally focus on women, including men is essential for achieving...

<p>Question</p><p>Prof G, could you do an article on what is going on with tolebrutinib in the States? Having a hard time processing the FDA rejection letter. Not sure what this means for the field.</p><p>NOTE: General...

<p>I keep getting pushback from people, including many colleagues, when I claim that the Epstein-Barr virus (EBV) is the cause of MS. This claim is based on a large body of epidemiological studies over the last 20 years...

<p>Several subscribers have asked me to comment on the new classification system for multiple sclerosis (MS) published last month in the journal Brain, which uses MRI and serum neurofilament levels. One person asked...

<p>Sylvia found us, and that is the primary learning point of this case study.</p><p>Sylvia was diagnosed with MS two months into an internship with an investment bank in London. She probably had an episode of optic...

<p>24th December 2025, Byfield, Northamptonshire</p><p>Mary lives alone. Her husband has long departed; he filed for a divorce and left the marital home more than a decade ago when Mary had to stop working. Mary has two...

<p>If you are a regular MS-Selfie reader, you will know that I am a proponent of the Epstein-Barr virus (EBV) theory of multiple sclerosis (MS). I am convinced that EBV is the cause of MS. EBV is necessary but...

<p>People with MS can report alterations of consciousness, self-perception, and reality testing. Among these neuropsychiatric phenomena, dissociative states—ranging from transient feelings of unreality to chronic...

<p>I just received a howler of an email from an MS-Selfie reader accusing me of neglecting people with primary progressive MS (pwPPMS) and of being a charlatan for running a subscription model. They concluded by asking...

<p>I have just returned from a lecture tour of Canada, which included four cities in four days and 12 speaking arrangements. My host's hospitality and kindness were exceptional. Thank you, thank you. I felt appreciated...

<p>Do we need to challenge the dogma that traditional MRI is good enough to monitor MS?</p><p>Our current treatment target in MS is no evident inflammatory disease activity or NEIDA. In other words, there should be no...

<p>A fact worth knowing</p><p>Did you know that people with MS who have a vascular comorbidity (smoking, obesity, hypercholesterolemia, hyperlipidemia, hypertension and/or established vascular disease) need to use a...

<p>The current dogma that is emerging in the field of immunology and multiple sclerosis (MS) is that a prophylactic EBV vaccine will create an older population of individuals susceptible to later wild-type EBV infection...

<p></p><p>My prediction is that we will prevent multiple sclerosis (MS) by accident, i.e. as a secondary outcome to a broader public health intervention.</p><p>Many stakeholders think we can run a randomised controlled...

<p>I have written about uncertainty and how it affects the minds of people with chronic diseases such as MS (please see ‘Uncertainty associated with MS: are you comfortable with it?’, 20-Apr-2024).</p><p>Uncertainty has...