Your hormones control everything —from energy levels to weight, mood, and overall health. But understanding them shouldn’t feel like decoding a medical textbook. Welcome to Hormones, Metabolism & You! , the podcast where board-certified endocrinologist Dr. Cassie Smith breaks down the science behind your body’s most powerful regulators. Each week, Dr. Smith tackles the real questions about metabolism, weight management, thyroid health, menopause, PCOS, insulin resistance, and more—giving you clear, actionable insights to take charge of your health. Whether you’re struggling with stubborn weight, feeling fatigued, or just want to optimize your well-being, this podcast is your go-to resource for evidence-based advice, practical tips, and expert interviews. It’s time to understand your hormones, master your metabolism, and feel your best—because when your body is in balance, you thrive! 🎧 Subscribe now and start your journey to better health!<
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What happens when you’re doing all the “right” things for your hormones and health, but you still don’t feel better? In this episode, I sit down with Dr. Neil Nathan to explore why underlying factors like mold, Lyme disease, inflammation, nervous system dysregulation, and detoxification challenges may complicate treatment. We also talk about why some patients react unexpectedly to hormones or supplements, how Dr. Nathan approaches complex chronic illness, and why looking beyond the obvious diagnosis can sometimes change the conversation. Topics We Cover in This Episode: Why hormone protocols don’t always work as expected How mold and Lyme may affect the immune system Why “detox” isn’t a one-size-fits-all approach What persistent or unusual symptoms may be telling you How inflammation can present differently from person to person What cytokine testing can reveal Why environmental exposure matters When it may be time to look deeper If you’ve experienced persistent symptoms, unexpected reactions to treatment, or the frustration of doing everything “right” and still not feeling better, this is a conversation you’ll want to hear. Resources & Links Connect with Dr. Neil Nathan: https://neilnathanmd.com/ Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/ Use code LISTEN10 for 10 % off your order on shopmodernendocrine.com Follow Dr. Cassie Smith & Modern Endocrine Website: https://www.modern-endocrine.com/ Instagram: https://www.instagram.com/modernendocrine_/ Facebook: https://www.facebook.com/ModernEndocrine ️ YouTube: https://www.youtube.com/@modernendocrine ️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en Newsletter: https://linktr.ee/modernendocrine ➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
129: Why Is Testosterone Still Off-Limits for Women?
Sep 20, 202649 min
Testosterone in women is finally getting more attention, but what does that actually mean for women and their care? In this episode, I sit down with Dr. Terri DeNeui to discuss the FDA’s focus on testosterone, why there still isn’t an FDA-approved testosterone treatment specifically for women, and the questions surrounding safety, dosing, and access. We also talk about symptoms of testosterone deficiency, why “normal” lab ranges don’t always tell the full story, and the larger conversation around medical freedom and individualized care. Topics We Cover in This Episode: Why testosterone matters for women What the FDA is currently considering Why testosterone remains a controlled substance When symptoms can appear Why “normal” labs may not tell the whole story How dosing and delivery methods matter Where medical freedom fits into the conversation Tune in to hear Dr. Terri DeNeui’s perspective on where women’s testosterone care stands today, what still needs to change, and what patients should be asking. Resources & Links Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/ Use code LISTEN10 for 10 % off your order on shopmodernendocrine.com Follow Dr. Cassie Smith & Modern Endocrine Website: https://www.modern-endocrine.com/ Instagram: https://www.instagram.com/modernendocrine_/ Facebook: https://www.facebook.com/ModernEndocrine ️ YouTube: https://www.youtube.com/@modernendocrine ️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en Newsletter: https://linktr.ee/modernendocrine ➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
128: Viral Hormone Trends: What’s Actually Worth Your Time?
Sep 13, 202643 min
Social media is full of hormone hacks promising better energy, easier weight loss, balanced hormones, and fewer symptoms. But how much of it is actually backed by science? In this episode, I’m breaking down seven viral trends, including cortisol cocktails, fiber maxing, pink salt, metabolism morning routines, and “hormone-balancing” foods, and separating reasonable health habits from overhyped claims. I also talk about the way social media approaches PCOS and perimenopause, and why oversimplifying complex hormone conditions can do more harm than good. If you’ve ever wondered whether the latest hormone trend is worth trying, this conversation will help you look at these claims with a little more context and a lot less TikTok influence. Topics We Cover in This Episode: Why cortisol cocktails aren't what they claim to be The problem with suddenly “fiber maxing” What pink salt can actually do for you Whether a metabolism morning routine works The truth behind “hormone-balancing” foods Why PCOS weight-loss advice needs more nuance When a viral trend may be masking a bigger issue Tune in, subscribe to Hormones, Metabolism and You, and share this episode with someone who could use a little more context the next time a hormone hack hits their feed. Resources & Links Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/ Use code LISTEN10 for 10 % off your order on shopmodernendocrine.com Follow Dr. Cassie Smith & Modern Endocrine Website: https://www.modern-endocrine.com/ Instagram: https://www.instagram.com/modernendocrine_/ Facebook: https://www.facebook.com/ModernEndocrine ️ YouTube: https://www.youtube.com/@modernendocrine ️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en Newsletter: https://linktr.ee/modernendocrine ➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
127: Birth Control Masterclass: The Mash-Up Every Woman Needs to Hear
Sep 6, 202648 min
In this mash-up episode, I’m bringing together key conversations about birth control, PCOS, PMS, and the hormonal changes women experience from their 20s through perimenopause. We unpack why birth control is so often used to manage symptoms, what it may be masking, and how hormones like estrogen, progesterone, testosterone, insulin, and cortisol all fit into the bigger picture. We also talk about the different birth control options women may consider as they get older and why the right approach can change throughout different stages of life. From painful and irregular periods to PCOS, weight struggles, low libido, anxiety, fatigue, and the transition into perimenopause, this mash-up brings together the questions women are asking and the answers they deserve to hear. Topics We Cover in This Episode: Why birth control may be masking more than you realize The hormone connection behind PCOS and weight struggles What your period could be trying to tell you Why your 30s and 40s can bring unexpected changes The connection between cortisol, insulin, and androgens When painful or irregular periods deserve a closer look How gut health and stress fit into the hormone picture Why the same treatment may not make sense at every age Tune in for the full mash-up and hear these conversations come together in one place. You may walk away with a very different perspective on birth control, your symptoms, and the questions you should be asking about your own health. Resources & Links Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/ Use code LISTEN10 for 10 % off your order on shopmodernendocrine.com Follow Dr. Cassie Smith & Modern Endocrine Website: https://www.modern-endocrine.com/ Instagram: https://www.instagram.com/modernendocrine_/ Facebook: https://www.facebook.com/ModernEndocrine ️ YouTube: https://www.youtube.com/@modernendocrine ️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en Newsletter: https://linktr.ee/modernendocrine ➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
126: Health Care is So Broken - 3 Typical Patient Cases
Aug 30, 202648 min
The healthcare system is not designed to keep you well, and I am done pretending that is okay. In this episode, I am breaking from the usual format to talk honestly about why I believe healthcare in the United States has become so reactive instead of preventative, and how that approach is leaving people sick, frustrated, and without answers. I share my perspective as both a patient and a provider, including the ways insurance companies, healthcare systems, limited appointment times, and a diagnosis-by-diagnosis approach can keep providers from looking at the whole person. I also explain why symptoms and lab results cannot always be viewed in isolation, because our bodies do not operate in silos. Then, I walk through three patient scenarios that I see repeatedly in my practice: a 19-year-old struggling with PCOS symptoms and insulin resistance, a woman in her 30s dealing with fatigue, weight gain, sleep issues and brain fog who was told her labs were normal, and a woman in her 40s experiencing perimenopausal symptoms who was told she was too young for hormones. These stories reveal just how much can be missed when we only look at whether a number falls inside a laboratory's "normal" range instead of asking whether it actually makes sense for the person sitting in front of us. Most importantly, I want you to leave this episode knowing that you are not crazy, your symptoms matter, and you can become your own best advocate when the system isn't listening. Topics We Cover in This Episode: Why "normal" lab results may not tell the whole story The connection between symptoms that seem completely unrelated What three very different patients had in common Why the approach to preventative care needs to change The piece of the puzzle that can be missed when diseases are treated separately Why some women are told they are fine when they know something isn't right What it really means to become your own best health advocate Why waiting until something is completely broken may be costing you years Resources & Links Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/ Use code LISTEN10 for 10 % off your order on shopmodernendocrine.com Follow Dr. Cassie Smith & Modern Endocrine Website: https://www.modern-endocrine.com/ Instagram: https://www.instagram.com/modernendocrine_/ Facebook: https://www.facebook.com/ModernEndocrine ️ YouTube: https://www.youtube.com/@modernendocrine ️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en Newsletter: https://linktr.ee/modernendocrine ➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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