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Explain Podcast

Hosted by explain.pod · science · EN-US

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About this Podcast:

The Podcast Explain is for everyone interested in DNA/RNA sequencing or technology in general. As Iuliia doesn't have a solid background in sequencing, she keeps asking "simple" - even silly at times - questions and Daniel gives his best to make us understand.

Pitch Analysis

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Contact path

Verified email

Booking probability

46%

Guest openness

Selective

Verified email on file
80/100
Required Score

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Questions about Explain Podcast

What is Explain Podcast about?

The Podcast Explain is for everyone interested in DNA/RNA sequencing or technology in general. As Iuliia doesn't have a solid background in sequencing, she keeps asking "simple" - even silly at times - questions and Daniel gives his best to make us understand.

What has Explain Podcast covered recently?

Recent episodes include "The Epigenetics Epic - Part 1" (9 October 2026, 51 minutes), "454.bio" (7 April 2026, 26 minutes), and "Special: other Nanopore Sequencing" (20 March 2026, 39 minutes).

How often does Explain Podcast publish?

Explain Podcast publishes roughly every few months, with episodes averaging 47 minutes across 29 episodes.

How hard is it to get booked on Explain Podcast?

Booking probability for Explain Podcast is 46%, and the host is rated Selective on guests. Explain Podcast requires a Pod Score of 80 or higher. Explain Podcast's contact route on record: verified email.

Who should pitch Explain Podcast?

The strongest fits for Explain Podcast are Scientific Research & Development. Explain Podcast has a science audience.

About the host

Explain Podcast is a science podcast with 29 episodes published.

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Recent episodes

Our AI reads these to draft pitches. Use them as grounding for a pitch that cites a real guest and a specific topic.

  • Oct 9, 202651 min

    A long time coming, but here it is! Introduction: https://medlineplus.gov/genetics/understanding/howgeneswork/epigenome/ Mechanisms: https://en.wikipedia.org/wiki/Epigenetics DNA packaging...

  • Explain Podcast

    454.bio

    Apr 7, 202626 min

    The open-source DIY Sequencer was here. Update: 454.bio is now dead, but the archives still have it: https://web.archive.org/web/20250723191639/https://454.bio/ Their GitHub: https://github.com/454bio Elements new...

  • Mar 20, 202639 min

    We have the same thing at home! - yes, but in worse, cheaper or both Qitan: https://pmc.ncbi.nlm.nih.gov/articles/PMC8985760/ https://www.qitantech.com/ The QPinnacle2: https://www.vcbeathealth.com/article/1821...

  • Mar 10, 202636 min

    Artificial Intelligence everywhere, and sometimes its useful. Correction: apparently the Biostar Handbook is not free anymore :( AlphaGenome: https://omicsomics.blogspot.com/2026/02/non-coding-dnas-alpha-moment.html...

  • Feb 20, 202625 min

    When do you get your Illumina sticker for your ONSO? This is the first part of a two-parts news roundup. PacBio News: https://aseq.substack.com/p/pacbio-sells-short-read-tech-to-illumina...

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  • Explain Podcast

    Array Sequencing

    Dec 23, 202542 min

    For when matching and sticking is enough to get Links: Nice Youtube explainer: https://www.youtube.com/watch?v=NgRfc6atXQ8 Another nice one: https://www.youtube.com/watch?v=4bOY2Oh5tEQ Explaining this and more...

  • Nov 18, 202543 min

    After 454 now the second try by Roche: Axelios. Preprint: https://www.biorxiv.org/content/10.1101/2025.02.19.639056v1 Read here about the PoC: https://www.pnas.org/doi/full/10.1073/pnas.1601782113 Current state (2025)...

  • Explain Podcast

    News: 23andMe

    Oct 2, 202522 min

    This time something different. Sources: https://www.23andme.com/privacy/ https://verbraucherschutzforum.berlin/2025-03-25/23andme-meldet-insolvenz-an-was-nutzer-jetzt-wissen-sollten-357738/...

  • Aug 6, 202557 min

    The science of white blood cells, and much more Chapters: 05:30 Immunology how? 22:05 22q11.2 deletion syndrome 34:30 Scientific collaboration 40:00 Data losses 50:00 Flip it! 53:00 outlook 2030 Links: mini-immunology...

  • May 28, 202546 min

    Sharing a flowcell, reinvented Chapters: - 00:00 usegalaxy.org - 07:55 Singular Genomics start - 21:55 Max Reads - 29:40 DNA Structure / ATAC-seq Setup galaxy on local hardware...

  • Apr 2, 202546 min

    Spinnin' bases on wafers to do mostly natural SBS Chapters: - 00:00 Ultima ePCR with beads - 07:10 Spinning the wafer, nucleotides, no blocking - 14:30 Ultima ppmSeq + Element UltraQ - 25:30 How Element UltraQ was born...

  • Jan 28, 202555 min

    Now Illuminas IP, previously PacBios, previously OMNIONE... Because only one type of nucleotide is not complicated enough Chapters: 01:35 Introducing old problems 15:30 More Phred, more better 34:40 QuickGen: genetic...

  • Aug 1, 20241h 12m

    Mixing up long and cheap ... soon we need to add "vs mid-reads" Chapters: 00:00:00 Intro 00:03:30 Florians history 00:13:50 Q&A Ressources for Bioinformatics 00:27:00 Long-read-tools.org 00:35:42 ONT || PacBio 00:57:00...

  • Jul 2, 202437 min

    Rolling in circles to make DNA yarns Chapters: 00:00 Bioinformatics Upper Crust Tools 04:04 STAR 05:00 MGI 15:00 Daniels first contact 20:00 Brief Market Overview 22:30 Short read market 26:00 DFG High Costs Sequencing...

  • May 27, 202448 minS2

    Who needs all bases anyway? Chapters: 00:00 Phasing 08:50 Not Sequencing, really 14:00 Bionano Saphyr Chip 26:00 Nabsys - going electric 29:30 Tools available 39:00 QuickGen with Iuliia: Transposons! Links: Small...

  • Mar 22, 20241h 11m

    Chapters: 00:00 Gambling 15:00 Bubbles 30:00 Holes 57:30 One more thing 1:07:00 Finale 1:08:00 Finale of season 1! Eric Chow explaining single cell sequencing: https://www.youtube.com/watch?v=k9VFNLLQP8c Overview of...

  • Feb 9, 20241h 11m

    Getting the most out of Machines Chapters: 00:00 PhiX 14:30 low complexity 19:30 UMIs 32:10 FastQC 43:00 MultiQC 56:40 PycoQC PhiX concentrations for loading a validation run...

  • Explain Podcast

    E8: Nanopore

    Jan 16, 202457 min

    Pushing spaghetti through holes Chapers: 00:00 Intro 11:15 Measuring Ions 17:00 Quality 23:00 Duplex 24:30 MinION 25:15 PromethION 28:20 Methylation 29:00 Direct RNA sequencing 38:25 Basecalling 46:00 Basecalling bias...

  • Explain Podcast

    E7: PacBio

    Dec 21, 202356 min

    Zipping rounds in zeptoliters Chapters: 00:00 Intro 07:00 Laser 09:00 Zeptoliters 13:30 Polymerase speed 19:00 Error rate 22:00 SMRT Cell 25:45 ccs 30:00 Fragment size 34:30 Megaruptor 38:20 Data flow 47:00 SVs 53:00...

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