Epigenetics - The Medicine Nobody Told You About

A podcast for intelligent people who’ve been told by doctors that nothing more can be done. Dr. Nicola Schmitz, epigenetic coach, shares the science behind why genes aren’t destiny and how lifestyle, stress, nutrition, and environment turn disease on or off. Through real stories and research-backed insights, you’ll learn what conventional medicine often misses about fertility, autoimmune conditions, burnout, and aging. Season one tells the story of how one diagnosis led to a complete life transformation. New episodes every Tuesday.

Epigenetics - The Medicine Nobody Told You About is a health podcast hosted by Dr. Nicola Schmitz, with 12 episodes on record and a Required Pod Score of 80. PitchCentric scores this show on Booking Probability, Listen Score, and live audience signals refreshed every 24 hours.

Dr. Nicola Schmitz hosts Epigenetics - The Medicine Nobody Told You About, a health show with 12 episodes published.

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  Episode #12

  Season 2, Episode 6: A Journey Through A Single Night

  Aug 18, 202632 min

  In this episode, I take you through one night of sleep, hour by hour. I talk about sleep as one of the most active biological states of the body: a time for memory consolidation, hormonal regulation, immune recalibration, glymphatic clearance, mitochondrial recovery, oxidative stress repair, and cellular maintenance. My aim is to move sleep out of the category of “rest” and into the category of essential biological work. Losing sleep is not only about being tired the next day. It changes what the body is able to repair, clear, regulate, and rebuild. Downloadable Document A supporting document for this episode is available here: The Sleep Audit If you are interested in becoming an Epigenetics Coach yourself, learn about my program here: The Certified Epigenetics Coach Training Sources Matthew Walker - Why We Sleep https://www.simonandschuster.com/books/Why-We-Sleep/Matthew-Walker/9781501144325 Reddy, O. C. & van der Werf, Y. D. - The Sleeping Brain: Harnessing the Power of the Glymphatic System Through Lifestyle Choices https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698404/ Chong, P. L. H. et al. - Sleep, Cerebrospinal Fluid, and the Glymphatic System https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821419/ Davinelli, S. et al. - Sleep and Oxidative Stress: Current Perspectives on the Role of Sleep in Cellular Homeostasis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199221/ Zou, Y. et al. - Nightshift Work Can Induce Oxidative DNA Damage: A Pilot Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184341/ Stay connected: Website: www.dr-nicolaschmitz.com Instagram: @alter._health Email: support@reply.dr-nicola-schmitz.com

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  Episode #11

  Season 2, Episode 5: Three Ways Stress Lives In A Body

  Aug 11, 202633 min

  In this episode, I talk about stress not as a vague feeling, but as biology. I describe three different stress patterns I have seen again and again: the high-functioning achiever who cannot feel the cost, the person who switches off but never truly resets, and the person whose nervous system is fragmented by constant demand. The chemistry may overlap - cortisol, adrenaline, inflammation, sleep disruption, neurotransmitter depletion, immune effects - but the way stress enters the body is not the same for everyone. This episode is about recognizing the pattern before trying to fix it. Sources Herman, J. P. et al. - Regulation of the Hypothalamic-Pituitary-Adrenocortical Stress Response https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867107/ Knezevic, E. et al. - The Role of Cortisol in Chronic Stress, Neurodegenerative Diseases, and Psychological Disorders https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10706127/ Cleveland Clinic - HPA Axis: What It Is and How It Works https://my.clevelandclinic.org/health/body/hypothalamic-pituitary-adrenal-hpa-axis Palma-Gudiel, H. et al. - Stress-Induced Epigenetic Changes in Humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971665/ Stay connected: Website: www.dr-nicolaschmitz.com Instagram: @alter._health Email: support@reply.dr-nicola-schmitz.com

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  Episode #10

  Season 2, Episode 4: The Journey Of A Single Marker

  Aug 4, 202643 min

  Today we do something different. We follow a single molecule on its actual journey, from a leaf of spinach growing in a field, through your gut wall, through your liver, through an enzyme called MTHFR that you may have heard about from genetic testing, into a single cell, all the way to a specific spot on a specific gene where it silences the gene it was made to silence. The journey is real. It is happening, in some version, in your body right now, trillions of times a second, with the molecules from the food you ate yesterday and this morning. And in most modern adults, the journey is failing at at least one point. Often at several. This episode shows you where those failure points are and what the pathway actually needs to run at full speed. If your blood work is normal but your energy is not, if your mood swings without obvious cause, if you carry unexplained fatigue that no doctor has been able to name, this is the episode that may explain it. Free download with this episode: Nutrients Almost Every Westerner Is Low In . A practical reference with the nutrients that support methylation, the best food sources, and notes on supplementation. For a personal conversation about your own methylation and where to start. Sources Choi, S. W. et al. - Modulation of DNA Methylation by One-Carbon Metabolism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375321/ Raghubeer, S. et al. - Methylenetetrahydrofolate Reductase, the One-Carbon Cycle, and Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703276/ Crider, K. S. et al. - Folate and DNA Methylation: A Review of Molecular Mechanisms and the Evidence for Folate’s Role https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262611/ Stover, P. J. - One-Carbon Metabolism–Genome Interactions in Folate-Associated Pathologies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777484/ Ben Lynch - Dirty Genes https://www.harpercollins.com/products/dirty-genes-ben-lynch Stay connected: Website: www.dr-nicolaschmitz.com Instagram: @alter._health Email: support@reply.dr-nicola-schmitz.com

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  Episode #9

  Season 2, Episode 3: The Fabric Of Your Life

  Jul 28, 202636 min

  Everything you do enters your body through four doors. The bloodstream, the nervous system, the hormonal cascade, and the microbiome. Every meal, every night of sleep, every stressful call, every walk, every drink of water passes through one of these four channels and becomes, on the other side, information for your cells. In this episode, we walk through each of the four doors and see how they actually work. We look at estrogen recycling and why the gut has more to do with hormones than most people realize. We meet a businessman whose morning routine looked perfect from the outside, and whose afternoons quietly undid everything he had built in the mornings. And we set up the bridge into the next episode, where we go deep into methylation, the switch behind everything else we have discussed. If you have ever wondered what actually happens to a meal or a stressful conversation once it enters your body, this is the episode where the machinery gets visible. If you are interested in becoming an Epigenetics Coach yourself, have a look here: Certified Epigenetics Coach Training Sources Hartley, T. R. et al. - Caffeine and Stress: Implications for Risk, Assessment, and Management of Hypertension https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101832/ Reis, C. E. G. et al. - Effects of Coffee Consumption on Glucose Metabolism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544578/ National Cancer Institute - Benzene and Cancer Risk https://www.cancer.gov/about-cancer/causes-prevention/risk/substances/benzene Centers for Disease Control and Prevention / NIOSH - Benzene: NIOSH Pocket Guide to Chemical Hazards https://www.cdc.gov/niosh/npg/npgd0049.html U.S. Environmental Protection Agency - Volatile Organic Compounds’ Impact on Indoor Air Quality https://www.epa.gov/indoor-air-quality-iaq/volatile-organic-compounds-impact-indoor-air-quality Joye, Y. - Some Reflections on the Relevance of Fractals for Art Therapy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147024/ Stay connected: Website: www.dr-nicolaschmitz.com Instagram: @alter._health Email: support@reply.dr-nicola-schmitz.com

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  Episode #8

  Season 2, Episode 2: Why Genes Are Not Your Destiny

  Jul 21, 202638 min

  If a doctor has ever told you that something runs in your family and there is nothing you can do about it, this episode is for you. Genetic risk is real. Genetic destiny is not. The gap between the two is where almost all of the useful work happens, and almost nobody is taught to see it. We look at penetrance, which is the technical word for how often a gene actually produces the trait it codes for. We look at the Dutch Hunger Winter studies, which showed that what one generation lives through can shape the biology of the next. And we walk through a client story about a woman who was tested for the BRCA1 gene and, after receiving her result, said something that stays with me: I have wasted twenty years. Free download with this episode: Family History Mapping , a structured guide to look at your own family history and see the patterns that actually matter. If you carry a family history that has been weighing on you, or you want to think about your own biology with better information, this is for you. Sources GeneReviews / NCBI Bookshelf - BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer https://www.ncbi.nlm.nih.gov/books/NBK1247/ National Cancer Institute - BRCA Gene Changes: Cancer Risk and Genetic Testing https://www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet Kuchenbaecker, K. B. et al. - Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers https://jamanetwork.com/journals/jama/fullarticle/2632503 Chen, S. & Parmigiani, G. - Meta-Analysis of BRCA1 and BRCA2 Penetrance https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267287/ Heijmans, B. T. et al. - Persistent Epigenetic Differences Associated with Prenatal Exposure to Famine in Humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579375/ Kaati, G., Bygren, L. O., & Edvinsson, S. - Cardiovascular and Diabetes Mortality Determined by Nutrition During Parents’ and Grandparents’ Slow Growth Period https://www.nature.com/articles/5200859 Vågerö, D. et al. - Paternal Grandfather’s Access to Food Predicts All-Cause and Cancer Mortality in Grandsons https://www.nature.com/articles/s41467-018-07617-9 Ben Lynch - Dirty Genes https://www.harpercollins.com/products/dirty-genes-ben-lynch Stay connected: Website: www.dr-nicolaschmitz.com Instagram: @alter._health Email: support@reply.dr-nicola-schmitz.com

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