S2Ep10: Interview with Dr. Maria Deza Leon
May 14, 202642mEp. 10S2
This interview followed a Keynote speech Dr. Deza Leon gave at the 2026 Hawk Talks Event at KU Edwards Campus on May 1.
Show notes
Updated 12 days ago · Refreshed hourly
education
Reprogrammed: A biotechnology Podcast
Hosted by Jack Treml · 🇺🇸 US · EN · 21 episodes
Where this show ranks
Episodes
21
Last ep.
12 days ago
Avg length
19m
Booking Probability™
37
Stretch.
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Estimated audience
,
Audience size not yet estimated
Listen Score
19
Niche reach.
Virality (30d)
48
Steady cadence.
Pitch Analysis
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Required Pod Score
80/ 100
PremiumEstablished thought leaders with verified media credentials.
Guest openness
Not signalled recentlyBest topics to pitch
education
About this podcast
Reprogrammed in a biotechnology podcast that explores a new topic every season through examining a series of seminal papers. This podcast supports a Selected Topics in Biotechnology course at the University of Kansas' Edwards Campus - but you don't need to be in that course to listen!
education
About the host
Jack Treml hosts Reprogrammed: A biotechnology Podcast, a education show with 21 episodes published.
Recent episodes
Our AI reads these to draft pitches
S2Ep9: What’s in the Box: the making of a damn fine vaccine
Apr 13, 202621m0
This episode looks at two papers, one a 2019 paper by Hassett et al. about optimizing Lipid Nanoparticles specifically for intramuscular mRNA vaccines. And a second, Laczko et al., from 2020, that shows what kind of immu
Show notes
S2Ep7: Something looks off here
Mar 29, 202620mEp. 7S2
This episode discusses the 2005 Kariko et al. paper about RNA immunogenicity.
Show notes
S2Ep6: How to Outpace a Killer Virus
Mar 9, 202619mEp. 6S2
In this episode, we explain why influenza is such a persistent threat—its segmented RNA genome enables antigenic drift and reassortment-driven “shift,” letting it change faster than traditional vaccines can be manufactur
Show notes
S2Ep5: The call is coming from inside the house
Mar 4, 202626mEp. 5S2
mRNA vaccines: when the call is coming from inside the house, discusses how the immune system knows what's going on inside of cells and how specific that knowledge is. This episode explains MHC Haplotype and how MHC rest
Show notes
Show me the CTLs
Feb 26, 202622mEp. 4S2
This episode explores an early mRNA vaccination study showing that injected RNA can be injected into the body, be translated into protein that is presented on MHC class I to generate an antigen-specific cytotoxic T-cell
Show notesProgrammable Immunity
Feb 17, 202615mEp. 12S1
This week on Reprogrammed, Jack and Annie tackle a key limitation in CAR T cell therapy for solid tumors: poor trafficking to the tumor site. Centered on the 2010 study by Craddock et al., this episode explores how engin
Show notesRational Design for persistence
Feb 17, 202625mEp. 11S1
In this episode, we examine the work of Roselli et al.1, who explore a critical frontier in CAR T cell engineering: how to build T cells that don’t just kill tumors effectively, but also survive, persist, and adapt in th
Show notesShifting Gears
Feb 17, 202611mEp. 10S1
Over the past episodes of Reprogrammed, we’ve followed the rapid evolution of CAR T cell therapy—from early experiments demonstrating that antibody-based chimeric receptors could trigger T cell activation and IL-2 produc
Show notesDude, where's my CAR construct?
Feb 17, 202613mEp. 9S1
Over the past episodes of Reprogrammed, we’ve followed the rapid evolution of CAR T cell therapy—from early experiments demonstrating that antibody-based chimeric receptors could trigger T cell activation and IL-2 produc
Show notesWhat? Another Brentjens paper?
Feb 17, 202611mEp. 8S1
Reprogrammed is a biotechnology podcast exploring the development of cell therapies, with this season focusing on CAR T cells in cancer treatment. The Brentjens et al. (2013) study marked a pivotal moment in the clinical
Show notesIL-15 and B7 co-stimulation
Feb 17, 202611mEp. 7S1
This podcast delves into the exciting world of cancer immunotherapy, focusing on the evolution of cancer vaccines and the recent surge of cell-based therapies. This series follows a string of primary research papers high
Show notesFirst Gen CAR T Cells
Feb 17, 202613mEp. 6S1
This podcast delves into the exciting world of cancer immunotherapy, focusing on the evolution of cancer vaccines and the recent surge of cell-based therapies. This series follows a string of primary research papers high
Show notesIncorporating co-stimulatory signaling in CAR T Cells
Feb 17, 202619mEp. 5S1
This podcast delves into the exciting world of cancer immunotherapy, focusing on the evolution of cancer vaccines and the recent surge of cell-based therapies. This series follows a string of primary research papers high
Show notesSeason2 Episode3: Tang et al. use a gene gun for plasmid DNA bombardment
Feb 15, 202618mEp. 3S2
This is the first paper to demonstrate that plasmid DNA injections elicited humoral immune responses and could therefore function as vaccines.
Show notesEp 4: Hijacking T Cells
Feb 10, 202614m0
This episode addresses the question of whether lymphocytes can be harvested, reprogrammed in their specificity for a selected tumor antigen ex vivo, and then re-administered to the patient to combat their cancer. The fir
Show notesEp 3: Th Model T of CAR T Cells
Feb 10, 202612mEp. 1S3
This episode addresses the question of whether lymphocytes directed against one specific tumor antigen can be manipulated to better combat cancer. The first paper, from 1989, examines cells initially generated in an anim
Show notesEp 2: Oh, you mean I'm getting cancer all the time?
Feb 10, 202623mEp. 2S1
Introduction of key papers:o 1974 article by Israel Penn, MD, on cancer in immune deficiencies.2020 article by Hegde et al. on dendritic cells and immune surveillance.• Framing question: “Does the immune system operate t
Show notesEp 1: Get in the CAR loser, we're curing cancer
Feb 10, 202627mEp. 1S1
This podcast delves into the exciting world of cancer immunotherapy, focusing on the evolution of cancer vaccines and the recent surge of cell-based therapies. It begins with a brief historical overview, highlighting the
Show notesEp 1: Making something out of Nothing
Feb 10, 202613mEp. 1S2
This episode relates to: the 1990 Wolff et al., paper in Science,247(4949 Pt 1):1465–1468. Direct Gene Transfer into Mouse Muscle in Vivo and the 1993 Ulmer et al., paper in Science, 259(5102):1745–1749. Heterologous pro
Show notesSponsors and advertisers
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Audience demographics
Age
25-54
Consumer type
Lifelong learners
Topics covered
education
Successful pitch examples
No public pitch examples yet for this show.
Generate your own personalised pitchBest industries to pitch Reprogrammed: A biotechnology Podcast for
Based on semantic analysis of episode topics and host coverage, this show is a strong guest fit for executives in:
Data Analytics & BImoderateMachine Learning & Data SciencemoderateProfessional DevelopmentmoderateGaming & EsportsmoderateBusiness Consultingmoderate
Industry fit is computed by PitchCentric using vector embeddings of the show's episode catalog.
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Frequently asked questions
How do I pitch Reprogrammed: A biotechnology Podcast as a podcast guest?
To pitch Reprogrammed: A biotechnology Podcast, visit https://podcasters.spotify.com/pod/show/jack-treml for contact information, then craft a tight one-paragraph hook that ties your expertise to a gap in their recent education coverage.
Who is the host of Reprogrammed: A biotechnology Podcast?
Reprogrammed: A biotechnology Podcast is hosted by Jack Treml. The show is categorised under education and has published 21 episodes.
How many episodes does Reprogrammed: A biotechnology Podcast have?
Reprogrammed: A biotechnology Podcast has published 21 episodes.
What topics does Reprogrammed: A biotechnology Podcast cover?
Reprogrammed: A biotechnology Podcast regularly covers education. It sits in the education category.
Is it hard to get booked on Reprogrammed: A biotechnology Podcast?
Reprogrammed: A biotechnology Podcast is accessible for guests with genuine education expertise. A personalised, episode-aware pitch will still outperform a generic one every time.
Is Reprogrammed: A biotechnology Podcast currently accepting guest pitches?
Reprogrammed: A biotechnology Podcast hasn't explicitly signalled guest openness in recent episodes. That doesn't rule out pitching. your hook just needs to be especially compelling and relevant to their recent content.
How long are Reprogrammed: A biotechnology Podcast episodes?
Episodes of Reprogrammed: A biotechnology Podcast average 19 minutes. a focused format where a clear narrative arc and tight preparation matter most.
What guest credentials does Reprogrammed: A biotechnology Podcast typically look for?
Our data rates Reprogrammed: A biotechnology Podcast's guest bar at 80/100 (Premium tier). Established thought leaders with verified media credentials. Sign in to PitchCentric to see how your own Pod Score compares against this show.
Methodology. Booking Probability™ blends Listen Score, 30-day Virality, open-to-guests detection, and Apple ratings. Data refreshed every 60 minutes. Listen Score and Booking Probability are calculated by PitchCentric. Last enriched 12 days ago.
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